Detalhe da pesquisa
1.
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Nature
; 538(7625): 344-349, 2016 Oct 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27602946
2.
CRISPR-Cas9-modified pfmdr1 protects Plasmodium falciparum asexual blood stages and gametocytes against a class of piperazine-containing compounds but potentiates artemisinin-based combination therapy partner drugs.
Mol Microbiol
; 101(3): 381-93, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27073104
3.
Identification of pathogen genomic variants through an integrated pipeline.
BMC Bioinformatics
; 15: 63, 2014 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-24589256
4.
Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation.
Nat Commun
; 14(1): 1455, 2023 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36927839
5.
Human Aurora kinase inhibitor Hesperadin reveals epistatic interaction between Plasmodium falciparum PfArk1 and PfNek1 kinases.
Commun Biol
; 3(1): 701, 2020 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33219324
6.
Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics.
Science
; 359(6372): 191-199, 2018 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29326268
7.
Esterase mutation is a mechanism of resistance to antimalarial compounds.
Nat Commun
; 8: 14240, 2017 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28106035
8.
Hexahydroquinolines are antimalarial candidates with potent blood-stage and transmission-blocking activity.
Nat Microbiol
; 2(10): 1403-1414, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28808258
9.
Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL), a Resistance Mechanism for Two Distinct Compound Classes.
ACS Infect Dis
; 2(11): 816-826, 2016 11 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27933786
10.
Whole Genome Shotgun Sequencing Shows Selection on Leptospira Regulatory Proteins During in vitro Culture Attenuation.
Am J Trop Med Hyg
; 94(2): 302-313, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26711524
11.
Mutations in the Plasmodium falciparum Cyclic Amine Resistance Locus (PfCARL) Confer Multidrug Resistance.
mBio
; 7(4)2016 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27381290
12.
High-Throughput Luciferase-Based Assay for the Discovery of Therapeutics That Prevent Malaria.
ACS Infect Dis
; 2(4): 281-293, 2016 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27275010
13.
UDP-galactose and acetyl-CoA transporters as Plasmodium multidrug resistance genes.
Nat Microbiol
; 1: 16166, 2016 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27642791
14.
A broad analysis of resistance development in the malaria parasite.
Nat Commun
; 7: 11901, 2016 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27301419
15.
Next-Generation Sequencing of Plasmodium vivax Patient Samples Shows Evidence of Direct Evolution in Drug-Resistance Genes.
ACS Infect Dis
; 1(8): 367-79, 2015 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26719854